We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Small Animal Ultrasonogrphy Core provides high frequency ultrasound for non-invasive, in vivo, real-time, high-resolution imaging of tissue structure and function in small animals.
Core provides Instrument Services for analysis of 1) endogenous metabolic pathway intermediates or biomarkers from biological fluids, cell cultures, and tissues using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS), 2) energy metabolism (cell bioenergetics) in living cells using a Seahorse Analyzer, and 3) biomarkers/metabolites to quantitate pathway intermediates using HPLC with 3 detector options (ECD, UV-VIS, FLR).
Flow Cytometry Core at John G. Rangos Sr. Research Center is a BSL2+ compliant cytometry analysis and sorting facility located at the John G. Rangos Sr. Research Center in Lawrenceville serving investigators from across the University of Pittsburgh.
Health Sciences Mass Spectrometry Core provides liquid chromatography high resolution mass spectrometry (LC-HRMS) services for metabolomics, lipidomics and proteomics. Expert staff provide assistance throughout the full lifespan of all projects from experimental design and sample preparation through statistical analysis and interpretation of datasets.
Drosophila Facility specializes in producing drosophila media in bulk and making it available to local investigators.
Gnotobiotic Animal Core Laboratory is a BSL2-compliant mouse facility providing isolators for studies requiring a controlled microbiotic environment. All husbandry and upkeep services are provided. Additional specialized support is also available.
Core offers services for custom synthesis and characterization of peptides, peptoids and small molecule constructs. The facility has extensive capabilities for technologically advanced custom modifications such as bioconjugations and targeted therapeutic strategies. State of the art HPLC and mass spectrometry capabilities as well as services in support of protein, siRNA, antibody and small molecule quantification and characterization are available
Small Biomarker Core provides accurate and sensitive quantitative analysis in biological samples, with or without sample processing, using state-of-the-art ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). In addition to well qualified assays for common targets, experienced, knowledgeable personnel can provide assay development for novel targets
Cell Imaging Core Laboratory at John G. Rangos Sr. Research Center offers cell imaging by confocal microscopy, including live cell as well as laser capture microdissection and LCM.
Facility provides access to cutting edge instrumentation for high resolution structural analysis of proteins, protein complexes, viruses, macromolecular assemblies, cellular organelles, and bacterial cells.
Core is dedicated to development and application of magnetic resonance imaging and magnetic resonance spectroscopy for medical and biological research. MRRC is whole-body imaging capable with specialty in anatomical MRI imaging of brain, spine, extremities, liver, bladder as well as functional MRI to study cognitive, sensory, and motor function in the brain.
Core provides consultation regarding study design, statistical analyses, power and sample size calculations and data collection for clinical and translational studies and grant applications. BERD offers consultation for collecting and managing data using the REDCap system. BERD also offers a series of workshops to provide essential elements involved in data collection, data management and creating reports for research studies.
Core for imaging from single plane acquisition, to Z-stacks and 3D reconstruction, and to live imaging on slides or in tissue culture dishes. Microscopes are user operated after intensive training and demonstration of proficiency.
Facility in the Department of the Geophysical Sciences features instruments including TESCAN LYRA3 field-emission scanning electron microscope (FESEM) with focused ion beam (FIB). It is equiped to do EDS, WDS, EBSD, etc.
Software toolkint as compiler for homomorphic encryption. Google MLIR-based toolchain for FHE compilers.
Software toolkit as extensible cross compiler and standardized benchmark suite enabling comparisons between Fully Homomorphic Encryption libraries. Cross compiler and standardized benchmarks for FHE computation that targets lattigo, HElib, PALISADE, Microsoft SEAL, and tfhe.
Software toolkit as Homomorphic Encryption evaluation platform with set of native benchmarks and library agnostic language. Used to evaluate fully homomorphic encryption across libraries implementing different HE schemes within some cases incomparable security.
Software toolkit as C++ framework that translates between nearly plain text style user programs and FHE computations. Marble FHE library that translates between user programs written close-to-plaintext-style and FHE computations based on underlying FHE crypto libraries.
Software toolkit to perform Fully Homomorphic Encryption operations on encrypted data set. FHE compiler for C++ that converts subset of C++ programs into FHE circuits implemented in various backend libraries.
Software toolkit as compiler for SEAL homomorphic encryption library. Automates away parts that require cryptographic expertise. Allows to write programs that operate on encrypted data without having access to the secret key. Native library written in C++ with bindings for Python. Both Linux and Windows are supported.