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NURSA Datasets contains data related to nuclear receptors and nuclear receptor coregulators. As of March 20, 2020, NURSA is succeeded by the Signaling Pathways Project (SPP). All NURSA-biocurated transcriptomic datasets have been preserved for data mining in SPP. All non-transcriptomic dataset NURSA content will be transferred to dkNET, with whom we are evaluating options for archiving this content.
(last updated: Jun 5, 2020)
This source has been archived. We are no longer crawling it or it is no longer updating with new data.
Data or Model Expression Molecule| DOI | Original Dataset | Title | Technique | Organism | Description | Tissue/Cell lines | |||
|---|---|---|---|---|---|---|---|---|---|
| 10.1621/datasets.01002 | Characterization of nuclear receptor corepressor complexes | Affinity Purification | Human | This dataset is a HeLa cell affinity purification-based profile of interacting factors for nuclear receptor corepressors. | HeLa | Not available | 2015-03-28 | ||
| 10.1621/d3Q9ogpDw6 | Analysis of the PGC1β/Ppargc1b-regulated transcriptome in IL-4 and IFNγ-treated mouse macrophages | Transcriptomic | House Mouse | Bone marrow-derived macrophages from wild type and PGC1β/Ppargc1b null mutant mice were treated with and without 10 ng/ml IL-4 or IFNγ for 12 h. | myeloid lineage, macrophages, bone marrow-derived | PMID:17671090 | Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM | 2015-12-10 | |
| 10.1621/datasets.04010 | Analysis of the steroid receptor coactivator-1 (SRC-1/Ncoa1), glucocorticoid receptor interacting protein-1 (GRIP1/Ncoa2) and p300/CBP interacting protein (pCIP/Ncoa3)-regulated transcriptomes in mouse liver | Transcriptomic | House Mouse | Livers were removed from 8 week old ovariectomized SRC-1/Ncoa1, GRIP1/Ncoa2 and pCIP/Ncoa3 null mutant and wild-type female mice. | whole liver | PMID:16423883 | Jeong JW, Kwak I, Lee KY, White LD, Wang XP, Brunicardi FC, O'Malley BW, DeMayo FJ | 2015-12-10 | |
| 10.1621/fl1TWZZjRA | GEO:GSE54532 | Time-course transcriptomic analysis of a panel of MET receptor tyrosine kinase-inhibited gastric cancer cell lines | Transcriptomic | Human | Gastric cancer cell lines (KATO II, Snu-5, MKN45 or OKAJIMA) were treated for a range of times between 2 h and 24 h with vehicle or 0.1 µM PHA-665752 (PHA665), a MET-specific small molecule inhibitor. | epithelium, OKAJIMA cells | PMID:24757178 | Lai A, Park M | 2015-12-10 |
| 10.1621/datasets.04004 | Analysis of the estrogen receptor-related receptor-α (ERRα/Esrra)-regulated transcriptome in IL-4 and IFNγ-treated mouse macrophages | Transcriptomic | House Mouse | Bone marrow-derived macrophages from wild type and ERRα/Esrra null mutant mice were treated with and without 10 ng/ml IL-4 or IFNγ for 12 h. | myeloid lineage, macrophages, bone marrow-derived | PMID:17671090 | Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM | 2015-12-10 | |
| 10.1621/LBxZCHOVp0 | GEO:GSE77345 | Analysis of the 17β-estradiol (17βE2)-regulated, HSD17B1-dependent transcriptome in T47D breast cancer cells | Transcriptomic | Human | Human T47D breast cancer cells were transfected with HSD17B1 siRNA or control siRNA for 48 h. Cells were subsequently treated with 1 nM 17βE2 or vehicle for 48 h. | epithelium, T47D cells | PMID:27544780 | Aak J, Calvo E, Lin S | 2016-09-14 |
| 10.1621/5nkDIR47uF | GEO:GSE49073 | Analysis of the TGFβ-regulated transcriptome in a mouse model of epithelial-to-mesenchymal transition | Transcriptomic | House Mouse | Mouse NMuMG mammary gland epithelial cells stably transfected with a vector expressing pericentromeric Major satellite repeat (MSR) sequences or a control empty vector were treated for 8 h with 5 ng/ml TGFβ or vehicle. | other, whole mammary gland | PMID:24239292 | Sandra P | 2016-09-15 |
| 10.1621/OzD9WkdLYj | GEO:GSE17561 | Analysis of the thyroid hormone receptor-α (TRα/THRA) and TRβ/THRB-regulated transcriptomes in human HepG2 hepatocellular carcinoma cells | Transcriptomic | Human | Human HepG2 hepatocellular carcinoma cells stably expressing TRα/THRA, TRβ/THRB, or empty vector were treated with or without 100 nM T3 for 6 h. | epithelium, HepG2 cells | PMID:19628582 | Chan IH, Privalsky ML | 2015-03-28 |
| 10.1621/mO3MKQsQv6 | Transcriptomic analysis of 17β-estradiol (17βE2)-treated MCF-7 cells | Transcriptomic | Human | Human MCF-7 breast cancer cells were treated for 24 h with or without 10 nM 17βE2. | epithelium, MCF-7 cells | PMID:16455494 | Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH | 2015-03-28 | |
| 10.1621/wGxM43bqxz | GEO:GSE15091 | Analysis of the androgen receptor (AR)-dependent transcriptome in PC3 prostatic carcinoma cells | Transcriptomic | Human | Human PC3 prostatic carcinoma cells transfected with AR expression vector or empty vector were treated with or without 1 nM R1881 for 24 h. | epithelium, PC3 cells | PMID:19668381 | Lin B | 2015-03-28 |
| 10.1621/bjApzcAHlG | Time- and dose-dependence analysis of the Tamoxifen (Tam)-regulated transcriptome in mouse liver | Transcriptomic | House Mouse | 10 week old male C57BL/6 mice were treated by oral gavage with and without 10 - 100 mg/kg body weight Tam for 2 h - 12 h prior to liver removal. | whole liver | PMID:20937368 | Lee MH, Kim JW, Kim JH, Kang KS, Kong G, Lee MO | 2015-03-28 | |
| 10.1621/datasets.04008 | GEO:GSE39507 | Analysis of the GW4604-dependent transcriptome in the intestine of the Cyp27a1 null mutant mouse | Transcriptomic | House Mouse | 3-4 month Cyp27a1 knockout mice were treated with or without two doses of 100 mg/kg body weight GW4064 by oral gavage 12 h apart. Mice were sacrificed and intestines were removed 2 h after the second dose. | other, whole mucosa | PMID:16473946 | Inagaki T, Kliewer SA | 2015-03-28 |
| 10.1621/datasets.04005 | Proteomic analysis of nuclear receptor coregulator complexes | Affinity Purification | Human | This dataset shows interacting proteins for nuclear receptor coregulators determined by affinity purification and mass spectroscopy. 15 mg total protein was used from Normal HeLa Cell nuclear extract. The salt concentration was 150-175 mM KCl. Antibodies were incubated with nuclear extract for 4 hours at 4°C. Beads (Protein A-sepharose, Amersham Pharmacia) were incubated for 1 hour at 4°C. 0.5% NP-40 was included in the wash. Detection was by Coomassie brilliant blue R. Please contact laboratory for information on specific antibodies. | HeLa | Not available | 2015-03-28 | ||
| 10.1621/datasets.04009 | GEO:GSE40775 | Analysis of the short heterodimeric partner (SHP/Nr0b2) and SHP/Lep-regulated transcriptomes in mouse liver | Transcriptomic | House Mouse | Livers were removed from 12 week old male mice in the following backgrounds: (1) wild type; (2) SHP/Nr0b2 KO; and (3) SHP/Nr0b2-Lep double KO. | whole liver | Wang L, Moore DD | 2015-03-28 | |
| 10.1621/QbSpGciVT2 | Acute time course and dose-dependence analysis of the dexamethasone (Dex)-regulated transcriptome in rat liver | Transcriptomic | Norway Rat | Livers were isolated from rats treated for 3 - 24 h with or without 500 µg - 50 mg/kg bw/d Dex. | whole liver | PMID:25313160 | Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H | 2016-05-04 | |
| 10.1621/xyZZLDZJDZ | Analysis of the estrogen receptor-α (ERα/Esr1)-regulated transcriptome in mouse liver | Transcriptomic | House Mouse | Livers were removed from three month old ERα/Esr1 null mutant and wild-type female C57BL/6J mice. | whole liver | PMID:16463047 | Bryzgalova G, Gao H, Ahren B, Zierath JR, Galuska D, Steiler TL, Dahlman-Wright K, Nilsson S, Gustafsson JA, Efendic S, Khan A | 2015-03-28 | |
| 10.1621/yKltg4k8br | Analysis of the dexamethasone (Dex)-regulated transcriptome in SaOS2 osteoblasts | Transcriptomic | Human | Human osteoblastic SaOS2 cells were treated with and without 10 nM Dex for 6 h. | osteoblasts, SaOS2 cells | PMID:20173306 | Azuma K, Urano T, Ouchi Y, Inoue S | 2015-03-28 | |
| 10.1621/RdJpfZvFp6 | Analysis of the phenobarbital (Phenb)-regulated transcriptome in HepaRG cells | Transcriptomic | Human | Six independent experiments were run in which liver hepatoma HepaRG cells were treated with and without Phenob (8mM) for 20 h. | hepatocytes, HepaRG cells | PMID:19159669 | Lambert CB, Spire C, Renaud MP, Claude N, Guillouzo A | 2015-03-28 | |
| 10.1621/endTZMGb6Z | GEO:GSE11324 | Timecourse analysis of the 17β-estradiol (17βE2) dependent transcriptome in MCF-7 breast cancer cells | Transcriptomic | Human | Human MCF-7 breast cancer cells were treated with 100 nM 17βE2 or vehicle for 3-12 h. | epithelium, MCF-7 cells | PMID:17013392 | Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS, Brown M | 2015-03-28 |
| 10.1621/lbPzmF6Pwq | GEO:GSE8238 | Transcriptomic analysis of progesterone (P4)-treated mouse ovary | Transcriptomic | Norway Rat | Newborn Sprague-Dawley rat ovaries dissected from pups less than 8 h old, were cultured in the presence or absence of 1 µM P4 for 48 h. | whole ovary | PMID:17127748 | Nilsson E, Stanfield J, Skinner M | 2015-03-28 |
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